Pinealon

What it is

Not established. Cell studies report less oxidative damage and cell death. A 2020 review proposes that it enters cells and binds histone proteins or RNA to change gene activity, an idea its authors present as an assumption, not a confirmed finding.

What it is studied for

Researchers test whether pinealon protects nerve cells under stress. Cell experiments measured oxidative damage and cell death, and in a rat study it was given to pregnant rats with raised homocysteine before their offspring's learning was tested.

What the evidence says

Mainly cell and animal studies

Cell and rat findings do not show benefits in people. Human data are small Russian reports; one study of 32 adults with organic brain syndrome reported mixed effects on ageing and blood markers, and its abstract describes no placebo group. No randomized placebo-controlled trial or sleep study of pinealon was found.

How it was studied

Laboratory studies added pinealon to cultured cells, and a rat study gave it to pregnant rats. A 2020 review describes oral use in Russian clinical reports; no published study of pinealon as a nasal spray, or of the store's sprays, was found.